SCHEMBL5507622

SCHEMBL5507622

Nc1cc(N)c(F)c(F)c1F

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.50
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.32
HDAC1 Q13547 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL998262 0.83 ALDH1A1 (0.38) PTK2ALDH1A1HDAC1HDAC6
SCHEMBL3046239 0.81 PTK2 (0.39) PTK2ALDH1A1
SCHEMBL28161584 0.78 CYP3A4 (0.46) ALDH1A1GAA
SCHEMBL10529865 0.78 POLB (0.36) PTK2ALDH1A1GAA
SCHEMBL1796298 0.78 ALOX15 (0.35) PTK2ALDH1A1GAA
SCHEMBL23830130 0.78 CA1 (0.30) PTK2
SCHEMBL8526012 0.78 GAA (0.50) PTK2ALDH1A1GAA
SCHEMBL10922033 0.76 GAA (0.48) PTK2ALDH1A1GAA
SCHEMBL5599364 0.76
SCHEMBL16037465 0.76 PTK2 (0.35) PTK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117211076-B Polyurethane glass fiber sleeve and preparation process 东莞市好易达新材料科技有限公司 2024-07-23 CN claimed
CN-117211076-A Polyurethane glass fiber sleeve and preparation process 东莞市好易达新材料科技有限公司 2023-12-12 CN claimed
CN-117211076-B Polyurethane glass fiber sleeve and preparation process 东莞市好易达新材料科技有限公司 2024-07-23 CN disclosed
CN-117211076-B Polyurethane glass fiber sleeve and preparation process 东莞市好易达新材料科技有限公司 2024-07-23 CN disclosed
CN-117211076-A Polyurethane glass fiber sleeve and preparation process 东莞市好易达新材料科技有限公司 2023-12-12 CN disclosed
CN-117211076-A Polyurethane glass fiber sleeve and preparation process 东莞市好易达新材料科技有限公司 2023-12-12 CN disclosed
CN-103228643-B As the benzoxazole derivative of histamine h 4 receptor part BIOPROJET (FR) 2015-11-25 CN disclosed
CN-100478364-C Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2009-04-15 CN disclosed
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed
CN-1732189-A Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2006-02-08 CN disclosed
US-6900294-B2 Reactive azo dyes preparation thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-05-31 US disclosed