Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 13/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571374 | 0.78 | HDAC8 (0.50) | DYRK1ADYRK2DYRK1BHDAC8CD38 | |
| SCHEMBL17701204 | 0.76 | DYRK1A (0.41) | DYRK1ADYRK2DYRK1BHDAC8CD38 | |
| SCHEMBL2722754 | 0.75 | DYRK1A (0.77) | DYRK1ADYRK2DYRK1BCD38MAPT | |
| SCHEMBL48894 | 0.73 | DYRK1A (0.55) | DYRK1ADYRK2DYRK1BCD38ATM | |
| SCHEMBL1872880 | 0.73 | DYRK1A (0.55) | DYRK1ADYRK2DYRK1BHDAC8CD38 | |
| SCHEMBL13354419 | 0.72 | CYP2A6 (0.50) | DYRK1ADYRK2DYRK1BCD38CHEK1 | |
| SCHEMBL17701181 | 0.72 | DYRK1A (0.41) | DYRK1ADYRK2DYRK1BHDAC8CD38 | |
| SCHEMBL999315 | 0.71 | HDAC8 (0.46) | DYRK1ADYRK2DYRK1BHDAC8CD38 | |
| SCHEMBL8309617 | 0.71 | CD38 (0.49) | DYRK1ADYRK2DYRK1BCD38MAPT | |
| SCHEMBL4541085 | 0.71 | CD38 (0.49) | DYRK1ADYRK2DYRK1BCD38MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |