Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 16/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445253 | 0.79 | MAPK1 (0.53) | ADORA2BADORA1ADORA2AMAPK1KDM4E | |
| SCHEMBL30463614 | 0.79 | MAPK1 (0.53) | ADORA2BADORA1ADORA2AMAPK1KDM4E | |
| SCHEMBL3061780 | 0.73 | ADORA2B (0.54) | ADORA2BADORA1ADORA2ATDP1KDM4E | |
| SCHEMBL4057562 | 0.73 | ADORA2B (0.61) | ADORA2BADORA1ADORA2AADORA3MAP4K4 | |
| SCHEMBL28758987 | 0.73 | ADORA2B (0.51) | ADORA2BADORA1ADORA2AMAPK1TDP1 | |
| SCHEMBL28135936 | 0.72 | ADORA2B (0.53) | ADORA2BADORA1ADORA2AKDM4EALDH1A1 | |
| SCHEMBL4049097 | 0.71 | ADORA2B (0.64) | ADORA2BADORA1ADORA2AADORA3MAP4K4 | |
| SCHEMBL3058599 | 0.70 | ADORA2B (0.57) | ADORA2BADORA1ADORA2ATDP1KDM4E | |
| SCHEMBL29769313 | 0.70 | TAAR1 (0.45) | ADORA1ADORA2AMAPK1TDP1KDM4E | |
| SCHEMBL4052108 | 0.70 | ADORA2B (0.61) | ADORA2BADORA1ADORA2AADORA3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |