Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | FPR3 | P25089 | 5/20 | 0.31 |
| ▸ | FPR2 | P25090 | 5/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12342269 | 0.81 | PDE10A (0.35) | SMN1; SMN2PDE10ATRPV3MAPK1ALDH1A1 | |
| SCHEMBL17203791 | 0.79 | — | — | |
| SCHEMBL19984742 | 0.79 | PDE10A (0.32) | PDE10A | |
| SCHEMBL21273281 | 0.79 | PDE10A (0.32) | PDE10A | |
| SCHEMBL19984737 | 0.79 | TRPV3 (0.34) | PDE10ATRPV3 | |
| SCHEMBL16426790 | 0.78 | CHRM4 (0.35) | MAPK1 | |
| SCHEMBL628736 | 0.78 | HCAR2 (0.39) | STAT3HTTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL628266 | 0.77 | GSK3B (0.34) | STAT3HTTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL20298764 | 0.76 | WDR5 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL20298979 | 0.76 | WDR5 (0.39) | HTTSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |