Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578708 | 0.78 | TAAR1 (0.48) | ERN1TAAR1KEAP1POLBMEN1 | |
| SCHEMBL30452061 | 0.75 | TAAR1 (0.45) | ERN1TAAR1KEAP1POLBMEN1 | |
| SCHEMBL27624055 | 0.75 | KEAP1 (0.49) | ERN1TAAR1KEAP1PTPN1POLB | |
| SCHEMBL19662062 | 0.74 | TAAR1 (0.58) | ERN1TAAR1KEAP1PTPN1POLB | |
| SCHEMBL6067949 | 0.74 | ERN1 (0.49) | ERN1TAAR1KEAP1PTPN1POLB | |
| SCHEMBL394300 | 0.71 | TAAR1 (0.76) | ERN1TAAR1KEAP1POLBMEN1 | |
| SCHEMBL419195 | 0.71 | TAAR1 (0.61) | ERN1TAAR1KEAP1POLBMEN1 | |
| SCHEMBL14067105 | 0.71 | TAAR1 (0.45) | ERN1TAAR1KEAP1PTPN1POLB | |
| SCHEMBL30060639 | 0.71 | KEAP1 (0.58) | ERN1TAAR1KEAP1MEN1MAPT | |
| SCHEMBL29679522 | 0.71 | ERN1 (0.64) | ERN1TAAR1KEAP1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |