Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062442 | 0.94 | REV1 (0.72) | REV1CHRNA7CA9CA2KMT2A | |
| SCHEMBL3165278 | 0.92 | REV1 (0.73) | REV1CHRNA7MEN1KMT2ARAB9A | |
| SCHEMBL3064361 | 0.88 | REV1 (0.66) | REV1CHRNA7CA9CA2KMT2A | |
| SCHEMBL3048990 | 0.87 | REV1 (0.77) | REV1CHRNA7MEN1KMT2ARAB9A | |
| SCHEMBL3668878 | 0.86 | REV1 (0.66) | REV1CHRNA7MEN1KMT2ARAB9A | |
| SCHEMBL3059029 | 0.86 | REV1 (0.62) | REV1CHRNA7MEN1KMT2AABCB1 | |
| SCHEMBL3050371 | 0.85 | REV1 (0.84) | REV1CHRNA7KMT2ARAB9AKDM4E | |
| Acetic Acid SCHEMBL3042417 | 0.84 | REV1 (0.60) | REV1CHRNA7CA9CA2MEN1 | |
| SCHEMBL3059243 | 0.84 | REV1 (0.78) | REV1CHRNA7MEN1KMT2ARAB9A | |
| SCHEMBL3052241 | 0.83 | REV1 (0.76) | REV1CHRNA7KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
| EP-2155192-A2 | TETRAHYDROISOQUINOLINES AS TUMOUR GROWTH INHIBITORS | Sterix Limited (GB) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008117061-A2 | TETRAHYDROISOQUINOLINES AS TUMOUR GROWTH INHIBITORS | STERIX LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | REV1 1520/4885CHRNA7 4760/4885CA9 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.