Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28727222 | 1.00 | KMT2A (0.40) | KMT2ASMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL28899832 | 0.95 | TSHR (0.40) | SMN1; SMN2TP53MAPTKDM4ETSHR | |
| SCHEMBL31575386 | 0.88 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL28727214 | 0.85 | MEN1 (0.37) | KMT2ASMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL13609926 | 0.83 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL12758251 | 0.83 | KDM4E (0.36) | SMN1; SMN2TP53MAPTKDM4ETSHR | |
| SCHEMBL14097777 | 0.80 | KDM4E (0.40) | KMT2ASMN1; SMN2TP53RAB9AKDM4E | |
| SCHEMBL24156033 | 0.80 | LMNA (0.44) | KMT2ASMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL14354775 | 0.80 | ALDH1A1 (0.42) | KMT2AMAPTNPC1RAB9ATSHR | |
| SCHEMBL14261086 | 0.79 | ALDH1A1 (0.38) | KMT2ATP53KDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582890-B | Cyanine modified compound, intermediate, preparation method and application thereof | 南京傅立叶生物医药科技有限公司 | 2023-06-20 | — | — | CN | disclosed |