Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502388 | 0.89 | ABCB1 (0.53) | KDM4EGAALMNATHRBKMT2A | |
| SCHEMBL10056749 | 0.89 | ABCB1 (0.53) | KDM4EGAALMNATHRBKMT2A | |
| SCHEMBL502387 | 0.89 | ABCB1 (0.53) | KDM4EGAALMNATHRBKMT2A | |
| SCHEMBL218433 | 0.83 | GAA (0.64) | KDM4EGAALMNATHRBKMT2A | |
| SCHEMBL218432 | 0.83 | GAA (0.64) | KDM4EGAALMNATHRBKMT2A | |
| SCHEMBL463556 | 0.82 | MAPT (0.52) | KDM4EGAALMNATHRBKMT2A | |
| SCHEMBL14141132 | 0.81 | CYP1A2 (0.50) | KDM4EGAALMNATHRBKMT2A | |
| SCHEMBL3560755 | 0.80 | MEN1 (0.65) | GAALMNAKMT2AMAPTATM | |
| SCHEMBL16361794 | 0.80 | MEN1 (0.65) | GAALMNAKMT2AMAPTATM | |
| SCHEMBL3560757 | 0.80 | MEN1 (0.65) | GAALMNAKMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114977-A1 | S1PR4 RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | TIAKI THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |