Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282100 | 1.00 | KMO (0.64) | KMOALDH1A1TP53KDM4EKDM6B | |
| SCHEMBL25234564 | 0.87 | KMO (0.47) | KMOALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL16094054 | 0.86 | KMO (0.54) | KMOALDH1A1KDM4EKDM6BTET3 | |
| Hydrochloric Acid SCHEMBL17293618 | 0.84 | KMO (0.53) | KMOALDH1A1KDM4EKDM6BTET3 | |
| SCHEMBL25242773 | 0.82 | ALDH1A1 (0.51) | KMOALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25232475 | 0.81 | KMO (0.60) | KMOALDH1A1KDM4EKDM6BTET3 | |
| SCHEMBL25174367 | 0.80 | KMO (0.72) | KMOALDH1A1KDM4EKDM6BTET3 | |
| SCHEMBL31151693 | 0.79 | ALDH1A1 (0.61) | KMOALDH1A1KDM4EKDM6BTET3 | |
| SCHEMBL202448 | 0.79 | ALDH1A1 (0.61) | KMOALDH1A1KDM4EKDM6BTET3 | |
| SCHEMBL3355376 | 0.78 | KMO (1.00) | KMOALDH1A1KDM4EKDM6BTET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114977-A1 | S1PR4 RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | TIAKI THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |