Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088342 | 1.00 | CTSK (0.46) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29088335 | 0.83 | CTSK (0.52) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30465000 | 0.83 | CTSK (0.52) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL19359627 | 0.82 | CTSK (0.56) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL20155052 | 0.82 | CTSK (0.56) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL19359642 | 0.82 | CTSK (0.56) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL10239618 | 0.82 | CTSK (0.56) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL23975141 | 0.79 | HDAC2 (0.42) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL10506791 | 0.72 | CTSK (0.45) | CTSKHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL23975144 | 0.71 | SMN1; SMN2 (0.46) | CTSKHDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472268-A | Compounds capable of binding to proteins and conjugates obtained from these compounds | MC SAF公司 | 2023-07-21 | — | — | CN | disclosed |