Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.70 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.46 |
| ▸ | CBLB | Q13191 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2489185 | 1.00 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| Hydrochloric Acid SCHEMBL28572838 | 1.00 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| Hydrochloric Acid SCHEMBL11232338 | 1.00 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| SCHEMBL16799499 | 0.98 | ZDHHC20 (0.72) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| SCHEMBL5713251 | 0.98 | ZDHHC20 (0.72) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| SCHEMBL16799012 | 0.98 | ZDHHC20 (0.72) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| SCHEMBL5713293 | 0.98 | ZDHHC20 (0.72) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| Bromide SCHEMBL3043714 | 0.97 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| Iodide SCHEMBL8779913 | 0.97 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTKMT2AATM | |
| Bromide SCHEMBL3046686 | 0.97 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407928-B2 | Organophilic clay based drilling fluids containing Gemini surfactant and polyacrylamide | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-08-09 | — | — | US | claimed |
| US-20200325381-A1 | ORGANOPHILIC CLAY BASED DRILLING FLUIDS CONTAINING GEMINI SURFACTANT AND POLYACRYLAMIDE | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2020-10-15 | — | — | US | claimed |
| EP-1732960-B1 | NOVEL HIGH MOLECULAR WEIGHT ASSOCIATIVE AMPHOTERIC POLYMERS AND USES THEREOF | SPCM SA (FR) | 2018-12-05 | — | — | EP | claimed |
| EP-2834320-B1 | NEW AQUEOUS FRACTURING FLUID COMPOSITION AND FRACTURING METHOD IMPLEMENTING THE FLUID | SPCM SA (FR) | 2018-02-21 | — | — | EP | claimed |
| US-9249352-B2 | Aqueous fracturing fluid composition and fracturing process using the composition | S.P.C.M. SA (FR) | 2016-02-02 | — | — | US | claimed |
| US-20130255954-A1 | NOVEL AQUEOUS FRACTURING FLUID COMPOSITION AND FRACTURING PROCESS USING THE COMPOSITION | S.P.C.M. SA (FR) | 2013-10-03 | — | — | US | claimed |
| US-7700702-B2 | High molecular weight associative amphoteric polymers and uses thereof | SNF S.A.S. (FR) | 2010-04-20 | — | — | US | claimed |
| US-11613686-B2 | Associative copolymers with hydrophobic quaternized (meth)acrylamide and (meth)acrylic acid derivatives | BASF SE (DE) | 2023-03-28 | — | — | US | disclosed |
| US-11407928-B2 | Organophilic clay based drilling fluids containing Gemini surfactant and polyacrylamide | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-08-09 | — | — | US | disclosed |
| CN-109070025-B | Method and device for preparing aqueous polymer solution | 巴斯夫欧洲公司 | 2022-06-07 | — | — | CN | disclosed |
| US-20210230331-A1 | ASSOCIATIVE COPOLYMERS WITH HYDROPHOBIC QUATERNIZED (METH)ACRYLAMIDE AND (METH)ACRYLIC ACID DERIVATIVES | BASF SE (DE) | 2021-07-29 | — | — | US | disclosed |
| US-11015106-B2 | Reusable high performance water based drilling fluids | WEATHERFORD TECHNOLOGY HOLDINGS, LLC (US) | 2021-05-25 | — | — | US | disclosed |
| EP-3802725-A1 | ASSOCIATIVE COPOLYMERS WITH HYDROPHOBIC QUATERNIZED (METH)ACRYLAMIDE AND (METH)ACRYLIC ACID DERIVATIVES | BASF SE (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-9249352-B2 | Aqueous fracturing fluid composition and fracturing process using the composition | S.P.C.M. SA (FR) | 2016-02-02 | — | — | US | disclosed |
| WO-2015052644-A1 | REUSABLE HIGH PERFORMANCE WATER BASED DRILLING FLUIDS | CLEARWATER INTERNATIONAL, LLC (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20150096808-A1 | REUSABLE HIGH PERFORMANCE WATER BASED | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2015-04-09 | — | — | US | disclosed |
| WO-2015024865-A1 | STABILISED COMPOSITIONS CONTAINING ACRYLAMIDE POLYMERS, AND METHOD FOR THE TERTIARY PRODUCTION OF CRUDE OIL USING SAID COMPOSITIONS | BASF SE (DE) | 2015-02-26 | — | — | WO | disclosed |
| US-20130255954-A1 | NOVEL AQUEOUS FRACTURING FLUID COMPOSITION AND FRACTURING PROCESS USING THE COMPOSITION | S.P.C.M. SA (FR) | 2013-10-03 | — | — | US | disclosed |
| US-7700702-B2 | High molecular weight associative amphoteric polymers and uses thereof | SNF S.A.S. (FR) | 2010-04-20 | — | — | US | disclosed |
| US-20070287815-A1 | Novel High Molecular Weight Associative Amphoteric Polymers And Uses Thereof | SNF SAS (FR) | 2007-12-13 | — | — | US | disclosed |