Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | NOS3 | P29474 | 2/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039866 | 1.00 | ASIC3 (1.00) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL9275978 | 0.96 | ASIC3 (0.91) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL12176988 | 0.87 | ASIC3 (0.77) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL12443810 | 0.84 | ASIC3 (0.72) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL21190506 | 0.82 | ASIC3 (0.69) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL901898 | 0.82 | ASIC3 (0.69) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL29601960 | 0.82 | ASIC3 (0.68) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL1073895 | 0.82 | ASIC3 (0.68) | ASIC3MEN1KMT2ARAB9ANOS3 | |
| SCHEMBL58442 | 0.82 | MEN1 (1.00) | ASIC3MEN1KMT2ARAB9AADORA2A | |
| SCHEMBL23110562 | 0.80 | ASIC3 (0.67) | ASIC3MEN1KMT2ARAB9ANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122754-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING GB13, GB22 AND HIMGALINE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |