Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22634017 | 0.94 | THRB (0.59) | THRBCA1CA2MMP1MMP2 | |
| Silver SCHEMBL30466744 | 0.92 | THRB (0.42) | THRB | |
| SCHEMBL4575999 | 0.88 | THRB (0.43) | THRB | |
| SCHEMBL29133533 | 0.85 | THRB (0.60) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL28376131 | 0.84 | THRB (0.48) | THRB | |
| SCHEMBL20478148 | 0.82 | THRB (0.65) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL28417455 | 0.82 | THRB (0.65) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL20478151 | 0.82 | THRB (0.65) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL28030131 | 0.82 | THRB (0.65) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL18937067 | 0.82 | THRB (0.65) | THRBCA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116195372-A | Metal electrode film and method for manufacturing same | CLAP有限公司 | 2023-05-30 | — | — | CN | disclosed |