Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20690112 | 0.98 | THRB (0.44) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL9336454 | 0.96 | THRB (0.48) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL22246156 | 0.96 | THRB (0.48) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL7816152 | 0.91 | THRB (0.36) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL5467545 | 0.81 | LIPA (0.38) | CA2GAAMGAMSIMGAM2 | |
| SCHEMBL412034 | 0.81 | THRB (0.56) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL11834156 | 0.81 | THRB (0.56) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL15271614 | 0.77 | THRB (0.46) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL2221105 | 0.76 | THRB (0.42) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL6377121 | 0.75 | THRB (0.45) | THRBCA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116195372-A | Metal electrode film and method for manufacturing same | CLAP有限公司 | 2023-05-30 | — | — | CN | disclosed |