Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.72 |
| ▸ | WNT3A | P56704 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15969098 | 0.84 | CTNNB1 (1.00) | CTNNB1WNT3A | |
| SCHEMBL21441179 | 0.80 | CTNNB1 (0.82) | CTNNB1WNT3ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27594531 | 0.79 | TUBB4A (0.67) | CTNNB1WNT3ATUBB4ATUBBTUBA3C | |
| SCHEMBL7266631 | 0.79 | KMT2A (0.62) | KMT2AHSD17B14F2MAPTRAB9A | |
| SCHEMBL7000679 | 0.79 | CTNNB1 (0.69) | CTNNB1WNT3AKMT2ATUBB4ATUBB | |
| SCHEMBL17927531 | 0.75 | ABL1 (0.49) | CTNNB1WNT3ATUBB4ATUBBTUBA3C | |
| 2-Picolinic Acid SCHEMBL10660099 | 0.75 | LMNA (0.62) | CTNNB1WNT3AKMT2AMAPTRAB9A | |
| SCHEMBL21834527 | 0.75 | DOT1L (0.62) | KMT2AHSD17B14MAPTRAB9ANPC1 | |
| SCHEMBL6447473 | 0.74 | F2 (0.59) | CTNNB1WNT3ATUBB4ATUBBTUBA3C | |
| Indole SCHEMBL3857973 | 0.74 | CTNNB1 (0.53) | CTNNB1WNT3AKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511730-B | Amide substituted indole compounds useful as TLR inhibitors | 百时美施贵宝公司 | 2023-07-25 | — | — | CN | disclosed |