Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21685510 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL21685481 | 0.84 | TDP1 (0.50) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL21685584 | 0.83 | GRM5 (0.36) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL21684862 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL202342 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL21685458 | 0.68 | ADORA3 (0.45) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL21685418 | 0.66 | KDM4E (0.56) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL7743268 | 0.66 | TSHR (0.61) | ALDH1A1MAPTTSHRCA12CA1 | |
| SCHEMBL3301528 | 0.65 | TSHR (0.45) | ALDH1A1KMT2AMAPTHTTTSHR | |
| SCHEMBL28597048 | 0.65 | NPC1 (0.64) | ALDH1A1MEN1KMT2AL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-B1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA INC (US) | 2025-02-26 | — | — | EP | disclosed |
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |