Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16906143 | 1.00 | MAPT (0.58) | MAPTLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL17049220 | 0.89 | MAPT (0.66) | MAPTLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL12992273 | 0.85 | GLO1 (0.52) | MAPTLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL7875955 | 0.84 | TDP1 (0.46) | MAPTLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL3591100 | 0.83 | KMT2A (0.53) | MAPTLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL3591104 | 0.83 | KMT2A (0.53) | MAPTLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL706410 | 0.83 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL706411 | 0.83 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7882366 | 0.82 | ALDH1A1 (0.71) | MAPTLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL7882365 | 0.82 | ALDH1A1 (0.71) | MAPTLMNAALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914234-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-06-23 | — | — | CN | disclosed |