Sugi Predict

Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL30467686

Nc1cnnc2cc(-c3cc(B(O)O)ccc3N3CCOCC3)ccc12.O=CO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LRRK2 Q5S007 4/20 0.39
▸ PDE10A Q9Y233 1/20 0.37
▸ PIK3CD O00329 3/20 0.33
▸ PIK3CA P42336 3/20 0.33
▸ PIK3CB P42338 2/20 0.33
▸ PIK3CG P48736 2/20 0.33
▸ CCNA2 P20248 1/20 0.33
▸ CDK2 P24941 1/20 0.33
▸ CCNA1 P78396 1/20 0.33
▸ NPC1 O15118 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ METAP2 P50579 1/20 0.32
▸ LCK P06239 1/20 0.32
▸ KIT P10721 1/20 0.32
▸ KDR P35968 1/20 0.32
▸ MAPK9 P45984 1/20 0.32
▸ MAPK14 Q16539 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ NCF1 P14598 1/20 0.32
▸ ERN1 O75460 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL25240502 1.00 LRRK2 (0.39) LRRK2PDE10APIK3CDPIK3CAPIK3CB
SCHEMBL24252619 0.95 PDE10A (0.40) LRRK2PDE10APIK3CDPIK3CAPIK3CB
Formic Acid SCHEMBL30467631 0.92 FEN1 (0.33) PIK3CDPIK3CAPIK3CBPIK3CGKDM4E
Formic Acid SCHEMBL25250167 0.92 FEN1 (0.33) PIK3CDPIK3CAPIK3CBPIK3CGKDM4E
SCHEMBL25240499 0.88 PDE10A (0.37) LRRK2PDE10APIK3CDPIK3CAPIK3CB
SCHEMBL26771355 0.88 PDE10A (0.41) LRRK2PDE10APIK3CDPIK3CAPIK3CB
SCHEMBL24252672 0.87 FEN1 (0.36) PDE10APIK3CDPIK3CAPIK3CBPIK3CG
Formic Acid SCHEMBL30462828 0.84 PLG (0.32) —
Formic Acid SCHEMBL25304448 0.84 PLG (0.32) —
SCHEMBL25250165 0.80 FEN1 (0.32) PIK3CDPIK3CAPIK3CBPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 — — US disclosed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 — — US disclosed
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON, INC. 2024-04-04 — — US disclosed
US-11814404-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2023-11-14 — — US disclosed
EP-4185592-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF Annexon, Inc. (US) 2023-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFB, CFH, C9 LRRK2 1477/4885PDE10A 1950/4885PIK3CD 1808/4885
US-11814404-B2 Inhibitors of complement factors and uses thereof CFB, CFH, C9 LRRK2 1477/4885PDE10A 1950/4885PIK3CD 1808/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH LRRK2 3700/4885PDE10A 3482/4885PIK3CD 3078/4885
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFH, CFB, C5 LRRK2 2687/4885PDE10A 2158/4885PIK3CD 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.