SCHEMBL30467925

SCHEMBL30467925

CN1CCC(F)(COc2ccc(S(=O)(=O)NC(=O)c3ccc(N4CCN(CC5=C(c6ccc(Cl)cc6)CC(C)(C)CC5)CC4)cc3Oc3cnc4[nH]ccc4c3)cc2Cl)CC1

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700600 1.00 BCL2 (0.88) BCL2
SCHEMBL1700452 0.94 BCL2 (0.89) BCL2
SCHEMBL30467973 0.94 BCL2 (0.89) BCL2
SCHEMBL30313895 0.94 BCL2 (1.00) BCL2
SCHEMBL1701665 0.94 BCL2 (1.00) BCL2
SCHEMBL30314055 0.93 BCL2 (1.00) BCL2
SCHEMBL1699870 0.93 BCL2 (1.00) BCL2
SCHEMBL1701487 0.93 BCL2 (0.86) BCL2
SCHEMBL31344636 0.93 BCL2 (0.86) BCL2
SCHEMBL1700602 0.90 BCL2 (0.78) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
EP-4218731-A2 MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT AbbVie Ireland Unlimited Company (IE) 2023-08-02 — — EP disclosed
Send feedback