Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227653 | 1.00 | GAA (1.00) | GAAMETAP1PDE3BPDE3ASRC | |
| SCHEMBL11044464 | 0.81 | GAA (0.68) | GAAMETAP1PDE3BPDE3ACYP11B1 | |
| SCHEMBL333847 | 0.78 | GAA (0.63) | GAASRCMAOAALDH1A1ACHE | |
| SCHEMBL5044573 | 0.76 | GAA (0.60) | GAAPDE3BPDE3ATDP2MAOB | |
| SCHEMBL21762103 | 0.74 | GAA (0.58) | GAAMETAP1PDE3BPDE3ASRC | |
| SCHEMBL28634068 | 0.74 | GAA (0.58) | GAASRCTDP2 | |
| SCHEMBL19038489 | 0.73 | GAA (0.58) | GAAMETAP1PDE3BPDE3ACYP11B1 | |
| SCHEMBL10232028 | 0.73 | GAA (0.57) | GAAMETAP1PDE3BPDE3ACYP11B1 | |
| SCHEMBL15906664 | 0.73 | GAA (0.57) | GAAMAOAALDH1A1ACHE | |
| SCHEMBL11045652 | 0.73 | GAA (0.57) | GAATDP2ALDH1A1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |