Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333847 | 0.88 | GAA (0.63) | GAABRD4CYP3A4MAPTCRHBP | |
| SCHEMBL11041542 | 0.82 | BRD4 (0.38) | GAABRD4TDP2NCOA1NCOA3 | |
| SCHEMBL15906664 | 0.82 | GAA (0.57) | GAABRD4ALDH1A1 | |
| Oxalic Acid SCHEMBL15319252 | 0.81 | GAA (0.56) | GAABRD4CYP3A4MAPTCRHBP | |
| SCHEMBL28634068 | 0.81 | GAA (0.58) | GAABRD4TDP2CYP3A4MAPT | |
| SCHEMBL13593675 | 0.76 | GAA (0.53) | GAABRD4CYP3A4MAPTCRHBP | |
| SCHEMBL3821050 | 0.75 | PARP1 (0.37) | BRD4TDP2NCOA1NCOA3CYP3A4 | |
| SCHEMBL11041593 | 0.75 | GAA (0.51) | GAABRD4CYP3A4MAPTMAPK1 | |
| SCHEMBL11043204 | 0.73 | BRD4 (0.44) | BRD4TDP2NCOA1NCOA3CYP3A4 | |
| SCHEMBL30468397 | 0.73 | GAA (1.00) | GAATDP2DRD5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |