Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856899 | 0.86 | HTT (0.37) | SMYD2HTTSMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL25062335 | 0.80 | SMYD2 (0.42) | SMYD2HTTSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL30955759 | 0.80 | SMYD2 (0.43) | SMYD2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL28917486 | 0.80 | SMYD2 (0.43) | SMYD2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL30726327 | 0.80 | SMYD2 (0.43) | SMYD2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL30955729 | 0.80 | SMYD2 (0.43) | SMYD2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL10236926 | 0.79 | SMYD2 (0.39) | SMYD2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL25329564 | 0.78 | SMYD2 (0.44) | SMYD2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL599980 | 0.77 | SMYD2 (0.48) | SMYD2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL599855 | 0.77 | SMYD2 (0.43) | SMYD2HTTSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |