Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
| ▸ | AHR | P35869 | 4/20 | 0.61 |
| ▸ | CMA1 | P23946 | 2/20 | 0.61 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | TDP2 | O95551 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398137 | 1.00 | CA9 (0.70) | CA9AHRCMA1EIF2AK2PDK2 | |
| Hydrochloric Acid SCHEMBL9833199 | 0.98 | CA9 (0.68) | CA9AHRCMA1EIF2AK2PDK2 | |
| Methylamine SCHEMBL28015139 | 0.96 | CA9 (0.66) | CA9AHRCMA1EIF2AK2PDK2 | |
| SCHEMBL22660 | 0.84 | AHR (0.61) | CA9AHRCMA1EIF2AK2PDK2 | |
| SCHEMBL28378777 | 0.83 | MAPT (0.62) | CA9AHRCMA1EIF2AK2TDP2 | |
| SCHEMBL29370621 | 0.82 | CA9 (1.00) | CA9KDM4EMEN1GAAMAPT | |
| Hydrochloric Acid SCHEMBL15206761 | 0.82 | AHR (0.59) | CA9AHRCMA1EIF2AK2PDK2 | |
| SCHEMBL521524 | 0.82 | CA9 (1.00) | CA9KDM4EMEN1GAAMAPT | |
| Bromide SCHEMBL9824774 | 0.82 | AHR (0.59) | CA9AHRCMA1EIF2AK2PDK2 | |
| SCHEMBL2616913 | 0.82 | TDP2 (0.54) | CA9AHRCMA1EIF2AK2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-110769821-B | Spiro indolines as IL-17 modulators | UCB生物制药有限责任公司 | 2023-07-07 | — | — | CN | disclosed |