Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21904287 | 1.00 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL21904551 | 0.82 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL21904555 | 0.81 | CALCRL (0.31) | — | |
| SCHEMBL259351 | 0.81 | NPC1 (0.32) | DGAT1 | |
| SCHEMBL29365567 | 0.81 | NPC1 (0.32) | DGAT1 | |
| SCHEMBL30976865 | 0.79 | — | — | |
| SCHEMBL21904458 | 0.78 | USP1 (0.33) | DGAT1 | |
| SCHEMBL30468499 | 0.78 | USP1 (0.33) | DGAT1 | |
| SCHEMBL30468538 | 0.75 | — | — | |
| SCHEMBL13735177 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140679-A1 | SPIROCYCLIC HPK1 ANTAGONISTS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-07-04 | — | — | WO | disclosed |
| CN-110769821-B | Spiro indolines as IL-17 modulators | UCB生物制药有限责任公司 | 2023-07-07 | — | — | CN | disclosed |