Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842236 | 1.00 | PRKCI (0.52) | PRKCICREBBPCA2CA12CA1 | |
| SCHEMBL7109894 | 0.83 | PRKCI (0.56) | PRKCICREBBPCA2NPC1RAB9A | |
| SCHEMBL1376911 | 0.83 | ALDH1A1 (0.52) | CA2CA12CA1CA4CA6 | |
| SCHEMBL1008508 | 0.81 | CDC25B (0.55) | CA2CA12CA1CA4CA6 | |
| SCHEMBL30508415 | 0.81 | PRKCI (0.53) | PRKCICREBBPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3090722 | 0.81 | PARP1 (0.50) | CA2CA12CA1CA4CA6 | |
| SCHEMBL1026788 | 0.81 | PRKCI (0.53) | PRKCICREBBPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL265937 | 0.80 | PRKCI (0.62) | PRKCICREBBPNPC1RAB9AMAPT | |
| SCHEMBL3022646 | 0.80 | MAPT (0.47) | PRKCINPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31495791 | 0.80 | PRKCI (0.62) | PRKCICREBBPNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558485-A1 | TEAD INHIBITORS AND METHODS OF USE | Sporos Biodiscovery, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-119497708-A | TEAD inhibitors and methods of use | 思博睿生物探索公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024020350-A1 | TEAD INHIBITORS AND METHODS OF USE | SPOROS BIODISCOVERY, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023161841-A1 | CHIRAL (P, N)-LIGAND FOR METAL COMPLEXES AND METHOD OF PREPARATION THEREOF | Indian Institute Of Science Education And Research Bhopal (IN) | 2023-08-31 | — | — | WO | disclosed |
| CN-113845548-B | Platinum complex of quinazoline hydrazine dithioformate and preparation method and application thereof | 深圳大学 | 2023-06-06 | — | — | CN | disclosed |