Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468765 | 1.00 | PRKCI (0.52) | PRKCICREBBPCA2CA12CA1 | |
| SCHEMBL7109894 | 0.83 | PRKCI (0.56) | PRKCICREBBPCA2NPC1RAB9A | |
| SCHEMBL1376911 | 0.83 | ALDH1A1 (0.52) | CA2CA12CA1CA4CA6 | |
| SCHEMBL1008508 | 0.81 | CDC25B (0.55) | CA2CA12CA1CA4CA6 | |
| SCHEMBL30508415 | 0.81 | PRKCI (0.53) | PRKCICREBBPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3090722 | 0.81 | PARP1 (0.50) | CA2CA12CA1CA4CA6 | |
| SCHEMBL1026788 | 0.81 | PRKCI (0.53) | PRKCICREBBPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL265937 | 0.80 | PRKCI (0.62) | PRKCICREBBPNPC1RAB9AMAPT | |
| SCHEMBL3022646 | 0.80 | MAPT (0.47) | PRKCINPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31495791 | 0.80 | PRKCI (0.62) | PRKCICREBBPNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558485-A1 | TEAD INHIBITORS AND METHODS OF USE | Sporos Biodiscovery, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-119497708-A | TEAD inhibitors and methods of use | 思博睿生物探索公司 | 2025-02-21 | — | — | CN | disclosed |
| US-20250026721-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| WO-2024020350-A1 | TEAD INHIBITORS AND METHODS OF USE | SPOROS BIODISCOVERY, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2024020350-A1 | TEAD INHIBITORS AND METHODS OF USE | SPOROS BIODISCOVERY, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| CN-113845548-B | Platinum complex of quinazoline hydrazine dithioformate and preparation method and application thereof | 深圳大学 | 2023-06-06 | — | — | CN | disclosed |
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |
| CN-109912434-B | Synthesis method of phenylethanolamine beta receptor agonist | 上海安谱实验科技股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-109912434-A | The synthetic method of phenyl ethyl amine beta receptor agonist | 上海安谱实验科技股份有限公司 | 2019-06-21 | — | — | CN | disclosed |
| EP-3040329-B1 | AROMATIC COMPOUND AND USE THEREOF IN THE TREATMENT OF DISORDERS ASSOCIATED WITH BONE METABOLISM | KYOTO PHARMA IND (JP) | 2018-10-10 | — | — | EP | disclosed |
| WO-1997035539-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
| US-4814350-A | HYPOGLYCEMIC | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| US-4754047-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0260400-A2 | Method of treating diabetes with 5-[1-hydroxy-2-(isopropylamino)-ethyl]anthranilonitrile | AMERICAN CYANAMID COMPANY (US) | 1988-03-23 | — | — | EP | disclosed |
| EP-0049728-B1 | METHOD FOR ENHANCING THE GROWTH RATE OF MEAT-PRODUCING ANIMALS AND FOR IMPROVING THE LEAN MEAT TO FAT RATIO THEREOF | AMERICAN CYANAMID COMPANY (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4522822-A | Phenylethane derivatives and acid addition salts thereof for increasing lean meat deposition and/or improving lean meat to fat ratio in warm blooded animals | AMERICAN CYANAMID COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4501751-A | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby | AMERICAN CYANAMID COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| US-4407819-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| US-4404222-A | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby | AMERICAN CYANAMID COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0049728-A2 | Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof | AMERICAN CYANAMID COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250026721-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | KRAS, HRAS, NRAS | PRKCI 244/4885CREBBP 410/4885CA2 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.