SCHEMBL30469259

SCHEMBL30469259

O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccnc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 18/20 1.00
CNR2 P34972 1/20 0.78
MEN1 O00255 1/20 0.72
RAB9A P51151 1/20 0.72
KMT2A Q03164 1/20 0.72
KDR P35968 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20557904 1.00 CNR1 (1.00) CNR1CNR2MEN1RAB9AKMT2A
SCHEMBL4911349 0.89 CNR1 (0.80) CNR1CNR2MEN1RAB9AKMT2A
SCHEMBL20557634 0.88 CNR1 (1.00) CNR1CNR2
SCHEMBL30469231 0.88 CNR1 (1.00) CNR1CNR2
SCHEMBL30469267 0.86 CNR1 (1.00) CNR1CNR2MEN1KMT2A
SCHEMBL20557649 0.86 CNR1 (1.00) CNR1CNR2MEN1KMT2A
SCHEMBL20557298 0.84 CNR1 (1.00) CNR1CNR2
SCHEMBL30469269 0.84 CNR1 (1.00) CNR1CNR2
SCHEMBL9190814 0.84 KMT2A (1.00) CNR1MEN1RAB9AKMT2A
SCHEMBL5186268 0.83 CNR1 (0.69) CNR1CNR2MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283668-A Diaryl ureas as CB1 allosteric modulators 研究三角协会 2023-06-23 CN claimed
CN-116283668-A Diaryl ureas as CB1 allosteric modulators 研究三角协会 2023-06-23 CN disclosed