Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.69 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921639 | 0.90 | CNR1 (0.71) | CNR1CNR2MAPT | |
| SCHEMBL30469259 | 0.83 | CNR1 (1.00) | CNR1CNR2KDRMEN1RAB9A | |
| SCHEMBL20557904 | 0.83 | CNR1 (1.00) | CNR1CNR2KDRMEN1RAB9A | |
| SCHEMBL5186258 | 0.82 | CNR1 (0.47) | CNR1CNR2MAPTKDR | |
| SCHEMBL1492983 | 0.81 | PORCN (0.69) | CNR1CNR2MAPTKDRRAB9A | |
| SCHEMBL4911349 | 0.80 | CNR1 (0.80) | CNR1CNR2MAPTKDRMEN1 | |
| SCHEMBL20557632 | 0.77 | CNR1 (1.00) | CNR1CNR2MAPT | |
| SCHEMBL30469222 | 0.77 | CNR1 (1.00) | CNR1CNR2MAPT | |
| SCHEMBL20557634 | 0.75 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL30469231 | 0.75 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786422-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | Prosidion Limited (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006018662-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | PROSIDION LIMITED (GB) | 2006-02-23 | — | — | WO | disclosed |