Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557478 | 1.00 | LMNA (0.52) | LMNATSHRRXRARXRBKEAP1 | |
| SCHEMBL2608412 | 0.92 | KEAP1 (0.59) | LMNATSHRRXRARXRBKEAP1 | |
| SCHEMBL1622291 | 0.87 | MAPT (0.56) | LMNATSHRKEAP1NFE2L2MAPT | |
| SCHEMBL30469256 | 0.87 | MAPT (0.56) | LMNATSHRKEAP1NFE2L2MAPT | |
| SCHEMBL13917955 | 0.83 | TSHR (0.52) | LMNATSHRKEAP1NFE2L2MAPT | |
| SCHEMBL6738366 | 0.82 | TSHR (0.76) | LMNATSHRMAPTALDH1A1NPC1 | |
| SCHEMBL179286 | 0.80 | PTPRC (0.63) | LMNATSHRKEAP1NFE2L2MAPT | |
| SCHEMBL31496742 | 0.80 | PTPRC (0.63) | LMNATSHRKEAP1NFE2L2MAPT | |
| SCHEMBL11392466 | 0.80 | TSHR (0.73) | LMNATSHRMAPTALDH1A1NPC1 | |
| Iodide SCHEMBL30804629 | 0.80 | TSHR (0.73) | LMNATSHRMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |