SCHEMBL30469458

SCHEMBL30469458

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc(OCCCN)c2n1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 1.00
CYP3A4 P08684 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29240417 1.00 STING1 (1.00) STING1CYP3A4
SCHEMBL29240487 0.97 STING1 (0.95) STING1CYP3A4
SCHEMBL30469456 0.97 STING1 (0.95) STING1CYP3A4
SCHEMBL21790381 0.91 STING1 (0.84) STING1CYP3A4
SCHEMBL21789787 0.91 STING1 (0.88) STING1
SCHEMBL30469461 0.89 STING1 (0.82) STING1
SCHEMBL19437693 0.88 STING1 (0.82) STING1
SCHEMBL30469470 0.88 STING1 (0.81) STING1
SCHEMBL30947787 0.87 STING1 (1.00) STING1CYP3A4
SCHEMBL29240412 0.87 STING1 (1.00) STING1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417486-A1 ASYMMETRIC BIS-BENZIMIDAZOLE STING AGONIST IMMUNOCONJUGATES AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2024-12-19 US disclosed
EP-4412660-A1 ASYMMETRIC BIS-BENZIMIDAZOLE STING AGONIST IMMUNOCONJUGATES AND USES THEREOF Bolt Biotherapeutics, Inc. (US) 2024-08-14 EP disclosed
CN-118265545-A Asymmetric bisbenzimidazole STING agonist immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2024-06-28 CN disclosed
WO-2023059544-A1 ASYMMETRIC BIS-BENZIMIDAZOLE STING AGONIST IMMUNOCONJUGATES AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2023-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240417486-A1 ASYMMETRIC BIS-BENZIMIDAZOLE STING AGONIST IMMUNOCONJUGATES AND USES THEREOF STING1, BID, MAVS STING1 1/4885CYP3A4 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.