Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 3/20 | 0.30 |
| ▸ | CLK2 | P49760 | 2/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30470212 | 1.00 | PRMT5 (0.39) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL25670004 | 1.00 | PRMT5 (0.39) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL24365117 | 1.00 | PRMT5 (0.39) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL25320666 | 1.00 | PRMT5 (0.39) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL29325096 | 0.89 | SLC6A4 (0.41) | ALDH1A1HSD17B10DYRK1ACLK4SLC6A2 | |
| SCHEMBL30470985 | 0.87 | PRMT5 (0.30) | PRMT5WDR77 | |
| SCHEMBL31506590 | 0.84 | DYRK1A (0.34) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL25324534 | 0.82 | ALDH1A1 (0.34) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL25324531 | 0.82 | ALDH1A1 (0.34) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL25327271 | 0.82 | ALDH1A1 (0.34) | PRMT5WDR77RIPK2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431378-A | Ring-fused compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119060035-A | Nitrogen-containing polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-118772164-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-10-15 | — | — | CN | disclosed |
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-08-22 | — | — | US | disclosed |
| WO-2024160058-A1 | OXALIC ACID DIAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 四川科伦博泰生物医药股份有限公司 | 2024-08-08 | — | — | WO | disclosed |
| CN-118359604-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | PRMT5 347/4885WDR77 1263/4885RIPK2 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.