SCHEMBL30471718

SCHEMBL30471718

C=CCOC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SSTR3 P32745 1/20 0.50
▸ TGM2 P21980 1/20 0.46
▸ CTSL P07711 4/20 0.46
▸ SIRT2 Q8IXJ6 6/20 0.42
▸ SIRT1 Q96EB6 6/20 0.42
▸ SIRT3 Q9NTG7 3/20 0.42
▸ SIRT5 Q9NXA8 2/20 0.42
▸ HTR2A P28223 1/20 0.42
▸ CTSB P07858 1/20 0.42
▸ PTPN1 P18031 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18788631 0.81 SSTR3 (0.65) SSTR3CTSLHTR2A
SCHEMBL18788630 0.81 SSTR3 (0.65) SSTR3CTSLHTR2A
SCHEMBL18102693 0.79 SSTR3 (0.51) SSTR3CTSLSIRT2SIRT1SIRT3
SCHEMBL25361958 0.79 SSTR3 (0.50) SSTR3CTSLSIRT2SIRT1SIRT3
SCHEMBL25361946 0.79 SSTR3 (0.50) SSTR3CTSLSIRT2SIRT1SIRT3
SCHEMBL26015625 0.79 SSTR3 (0.48) SSTR3CTSLSIRT2SIRT1SIRT3
SCHEMBL16847750 0.79 SIRT2 (0.44) SSTR3TGM2CTSLSIRT2SIRT1
SCHEMBL29549580 0.78 PTPN1 (0.42) TGM2CTSLHTR2ACTSBPTPN1
SCHEMBL25361716 0.77 PTPN1 (0.43) SSTR3TGM2CTSLSIRT2SIRT1
SCHEMBL25361722 0.77 PTPN1 (0.43) SSTR3TGM2CTSLSIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170256-A1 THERAPEUTIC ANTIBODY AND USES THEREOF MULTITUDE THERAPEUTICS INC. (CN) 2025-05-29 — — US disclosed
US-20240010743-A1 THERAPEUTIC ANTIBODY AND USES THEREOF MULTITUDE THERAPEUTICS INC. (CN) 2024-01-11 — — US disclosed
CN-112105643-B Therapeutic antibodies and uses thereof 普众发现医药科技(上海)有限公司 2023-09-26 — — CN disclosed
EP-4204452-A1 THERAPEUTIC ANTIBODY AND USES THEREOF Multitude Inc. (CN) 2023-07-05 — — EP disclosed
CN-116323678-A Therapeutic antibodies and uses thereof 普众发现医药科技(上海)有限公司 2023-06-23 — — CN disclosed
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