SCHEMBL29549580

SCHEMBL29549580

C=CCOC(=O)NCCCC[C@@H](C(N)=O)N(C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)OCC=C)c1ccc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 1/20 0.42
▸ TGM2 P21980 1/20 0.42
▸ HTR2A P28223 1/20 0.39
▸ CTSL P07711 6/20 0.39
▸ P2RX7 Q99572 1/20 0.37
▸ DPP8 Q6V1X1 1/20 0.36
▸ DPP9 Q86TI2 1/20 0.36
▸ CTSB P07858 1/20 0.35
▸ CPB1 P15086 1/20 0.35
▸ CPB2 Q96IY4 1/20 0.35
▸ MMP1 P03956 1/20 0.35
▸ MMP2 P08253 1/20 0.35
▸ MMP7 P09237 1/20 0.35
▸ MMP9 P14780 1/20 0.35
▸ MMP8 P22894 1/20 0.35
▸ MMP14 P50281 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549748 0.91 TGM2 (0.42) PTPN1TGM2HTR2ACTSLP2RX7
SCHEMBL30471718 0.78 SSTR3 (0.50) PTPN1TGM2HTR2ACTSLCTSB
SCHEMBL3726655 0.76 TGM2 (0.46) TGM2CTSLP2RX7CTSBMMP1
SCHEMBL29522093 0.76 PTPN1 (0.40) PTPN1TGM2CTSLP2RX7
SCHEMBL28538964 0.73 HTR2A (0.49) TGM2HTR2ADPP8DPP9
SCHEMBL15669247 0.72 HTR2A (0.35) PTPN1TGM2HTR2ADPP8DPP9
SCHEMBL15669378 0.71 HTR2A (0.40) PTPN1TGM2HTR2AMMP1MMP2
SCHEMBL17161225 0.71 HTR2A (0.44) TGM2HTR2ADPP8DPP9
SCHEMBL2028970 0.68 TGM2 (0.62) TGM2DPP8DPP9MMP2MMP9
SCHEMBL34467666 0.68 TGM2 (0.61) TGM2DPP8DPP9MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098621-A1 ENGINEERED ANTIBODY WITH SITE-SPECIFIC CONJUGATION, ANTIBODY-DRUG CONJUGATE, AND APPLICATION THEREOF 百力司康生物医药(杭州)有限公司 2026-05-15 — — WO claimed
US-12605457-B2 Modified EGFR antibody with reduced affinity, drug conjugate, and use thereof Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2026-04-21 — — US claimed
US-20240342304-A1 Tetravalent Antibody-Drug Conjugates and Use Thereof BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2024-10-17 — — US claimed
US-11951173-B2 Tetravalent antibody-drug conjugates and use thereof Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2024-04-09 — — US claimed
US-20240075154-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2024-03-07 — — US claimed
US-20240009318-A1 MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2024-01-11 — — US claimed
US-20240002527-A1 ANTI-CD73 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2024-01-04 — — US claimed
US-20230414781-A1 ANTI-CD276 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2023-12-28 — — US claimed
EP-4247855-A1 ANTI-CD73 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
EP-4247854-A1 ANTI-CD276 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
EP-4247853-A1 MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
EP-4247425-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
CN-116528911-A anti-CD 73 antibody, antibody-conjugated drug and application thereof 百力司康生物医药(杭州)有限公司 2023-08-01 — — CN claimed
CN-116419929-A Engineered EGFR antibodies with reduced affinity, drug conjugates and uses thereof 百力司康生物医药(杭州)有限公司 2023-07-11 — — CN claimed
CN-116406382-A anti-CD 276 antibody, antibody-conjugated drug and application thereof 百力司康生物医药(杭州)有限公司 2023-07-07 — — CN claimed
WO-2022104692-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105878-A1 MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105879-A1 ANTI-CD276 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105873-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105881-A1 ANTI-CD73 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605457-B2 Modified EGFR antibody with reduced affinity, drug conjugate, and use thereof EGFR, ERBB2, IGSF11 PTPN1 653/4885TGM2 790/4885HTR2A 2751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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