Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25989026 | 0.98 | L3MBTL1 (0.76) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| SCHEMBL29023287 | 0.97 | L3MBTL1 (0.74) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| SCHEMBL5244961 | 0.85 | TSHR (1.00) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| Lithium Ion SCHEMBL25350249 | 0.84 | L3MBTL1 (0.61) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| SCHEMBL24194404 | 0.82 | L3MBTL1 (0.58) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| SCHEMBL3717775 | 0.74 | POLB (0.56) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| SCHEMBL3719691 | 0.73 | L3MBTL1 (0.52) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| SCHEMBL15832924 | 0.72 | MMP8 (0.87) | L3MBTL1TSHRMMP8MMP12MMP13 | |
| SCHEMBL5245574 | 0.72 | POLB (0.74) | L3MBTL1TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL17147370 | 0.72 | MMP8 (0.57) | L3MBTL1TSHRMMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323606-A | Azetidine derivatives for the treatment of integrin-associated diseases | 诺丁汉大学 | 2023-06-23 | — | — | CN | disclosed |