Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616681 | 1.00 | MAPT (0.39) | MAPTNPSR1ALDH1A1LMNAALOX12 | |
| SCHEMBL28534462 | 0.87 | MAPT (0.39) | MAPTNPSR1ALDH1A1LMNAALOX12 | |
| SCHEMBL28534509 | 0.86 | MAPT (0.38) | MAPTNPSR1ALDH1A1LMNAALOX12 | |
| SCHEMBL28531773 | 0.84 | ENPP2 (0.44) | MAPTNPSR1ENPP2TGM2RAB9A | |
| SCHEMBL28525708 | 0.84 | ENPP2 (0.44) | MAPTNPSR1ENPP2TGM2RAB9A | |
| SCHEMBL21619928 | 0.82 | ACACB (0.39) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL21616683 | 0.82 | ACACB (0.39) | MAPTACACBTACR1TACR3L3MBTL1 | |
| SCHEMBL30474510 | 0.82 | ACACB (0.39) | MAPTACACBTACR1TACR3L3MBTL1 | |
| SCHEMBL28526816 | 0.78 | KDM4E (0.42) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL28547084 | 0.77 | SMN1; SMN2 (0.42) | MAPTLMNAHPGDACACBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |