Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 18/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25214555 | 1.00 | HDAC2 (0.45) | HDAC2HDAC3HDAC1 | |
| SCHEMBL31108977 | 0.86 | HDAC2 (0.50) | HDAC2HDAC3HDAC1 | |
| SCHEMBL30474675 | 0.86 | HDAC2 (0.44) | HDAC2HDAC3HDAC1 | |
| SCHEMBL25252861 | 0.86 | HDAC2 (0.44) | HDAC2HDAC3HDAC1 | |
| SCHEMBL25214954 | 0.86 | MMP8 (0.36) | HDAC2HDAC1 | |
| SCHEMBL31109072 | 0.85 | HDAC2 (0.48) | HDAC2HDAC3HDAC1 | |
| SCHEMBL25249794 | 0.85 | HDAC2 (0.52) | HDAC2HDAC3HDAC1 | |
| SCHEMBL30474714 | 0.85 | HDAC2 (0.52) | HDAC2HDAC3HDAC1 | |
| SCHEMBL25249960 | 0.84 | HDAC2 (0.57) | HDAC2HDAC3HDAC1 | |
| SCHEMBL25256265 | 0.83 | HDAC2 (0.49) | HDAC2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4441033-A1 | NOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | Tango Therapeutics, Inc. (US) | 2024-10-09 | — | — | EP | disclosed |
| WO-2023102162-A1 | TGONOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |