SCHEMBL30475520 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	ACE	P12821	14/20	0.59

▸	MME	P08473	10/20	0.59

▸	CPA1	P15085	10/20	0.59

▸	ACE2	Q9BYF1	10/20	0.59

▸	LMNA	P02545	1/20	0.47

▸	TDP1	Q9NUW8	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30411925	0.86	LMNA (0.50)	ACEMMECPA1ACE2LMNA
SCHEMBL29601051	0.83	LMNA (0.52)	ACEMMECPA1ACE2LMNA
SCHEMBL157547	0.82	MME (0.61)	ACEMMECPA1ACE2
SCHEMBL8823249	0.81	MME (0.54)	ACEMMECPA1ACE2LMNA
SCHEMBL2780445	0.81	LMNA (0.54)	ACEMMECPA1ACE2LMNA
SCHEMBL2780446	0.81	LMNA (0.54)	ACEMMECPA1ACE2LMNA
SCHEMBL25284015	0.78	MME (0.62)	ACEMMECPA1ACE2LMNA
SCHEMBL28286750	0.78	MME (0.62)	ACEMMECPA1ACE2LMNA
SCHEMBL15692294	0.78	MME (0.57)	ACEMMECPA1ACE2
SCHEMBL15692326	0.78	ACE (0.68)	ACEMMECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024195825-A1	CEREBRAL ATROPHY ASSESSMENT METHOD USING BLOOD METABOLOME	味の素株式会社	2024-09-26	—	—	WO	disclosed
WO-2023130538-A1	TRACE SAMPLE-BASED METHOD FOR HIGH-THROUGHPUT RECOGNITION OF TRACE ORGANIC POLLUTANTS IN BLOOD	南京大学	2023-07-13	—	—	WO	disclosed