Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 4/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475872 | 0.92 | MMP1 (0.44) | PTPN1MMP1FCER2 | |
| SCHEMBL30799841 | 0.91 | BACE1 (0.53) | PTPN1BACE1 | |
| SCHEMBL30799481 | 0.90 | BACE1 (0.51) | PTPN1BACE1BACE2 | |
| SCHEMBL30799953 | 0.90 | BACE1 (0.51) | BACE1BACE2 | |
| SCHEMBL18286725 | 0.90 | BACE1 (0.46) | PTPN1BACE1 | |
| SCHEMBL30799262 | 0.89 | BACE1 (0.51) | PTPN1BACE1BACE2 | |
| SCHEMBL30799513 | 0.89 | BACE1 (0.49) | PTPN1BACE1BACE2CALCRL | |
| SCHEMBL30799430 | 0.89 | BACE1 (0.45) | PTPN1BACE1BACE2 | |
| SCHEMBL30799391 | 0.88 | BACE1 (0.54) | PTPN1BACE1BACE2 | |
| SCHEMBL31534594 | 0.87 | MME (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212549-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212549-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | FIBP, FN1, TPX2 | PTPN1 732/4885BACE1 2744/4885BACE2 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.