Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.71 |
| ▸ | BLM | P54132 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | HTR1A | P08908 | 4/20 | 0.71 |
| ▸ | HTR2A | P28223 | 4/20 | 0.71 |
| ▸ | HTR2C | P28335 | 4/20 | 0.71 |
| ▸ | HTR2B | P41595 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | HTR7 | P34969 | 2/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788031 | 1.00 | NPSR1 (0.71) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL10407441 | 0.87 | NPSR1 (0.69) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL10407439 | 0.87 | NPSR1 (0.69) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL3073308 | 0.86 | NPSR1 (0.65) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL5121693 | 0.86 | NPSR1 (0.67) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL29804259 | 0.86 | HDAC8 (0.77) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL20168578 | 0.86 | HDAC8 (0.77) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL20168582 | 0.86 | HDAC8 (0.77) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL20271388 | 0.84 | HTR2C (0.72) | NPSR1BLMALDH1A1LMNATSHR | |
| SCHEMBL8699875 | 0.84 | KDM4E (0.69) | BLMLMNATSHRHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2983473-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS Mountain Llc (US) | 2016-02-17 | — | — | EP | claimed |
| US-20140350064-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC | 2014-11-27 | — | — | US | claimed |
| WO-2014144130-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC (US) | 2014-09-18 | — | — | WO | claimed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | claimed |
| EP-1789052-A4 | COMPOSITION AND METHOD FOR INDUCING OR RESTORING LOCOMOTOR FUNCTIONS IN AN ANIMAL | UNIV LAVAL (CA) | 2008-05-21 | — | — | EP | claimed |
| US-20080096847-A1 | Composition And Method For Inducing Or Restoring Locomotor Functions In An Animal | UNIVERSITE LAVAL | 2008-04-24 | — | — | US | claimed |
| EP-1789052-A1 | COMPOSITION AND METHOD FOR INDUCING OR RESTORING LOCOMOTOR FUNCTIONS IN AN ANIMAL | Université Laval (CA) | 2007-05-30 | — | — | EP | claimed |
| WO-2006026850-A1 | COMPOSITION AND METHOD FOR INDUCING OR RESTORING LOCOMOTOR FUNCTIONS IN AN ANIMAL | UNIVERSITE LAVAL (CA) | 2006-03-16 | — | — | WO | claimed |
| US-20030187055-A1 | Synergistic pharmaceutical combinations for treating obesity | BANK OF AMERICA, N.A., AS AGENT | 2003-10-02 | — | — | US | claimed |
| US-20030162725-A1 | Synergistic pharmaceutical combinations for treating obesity with EGCG | BANK OF AMERICA, N.A., AS AGENT | 2003-08-28 | — | — | US | claimed |
| US-6579899-B1 | Precursor or prodrug of serotonin, tryptophan or 5-hydroxytryptophan | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-06-17 | — | — | US | claimed |
| WO-2002038141-A9 | COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-02-13 | — | — | WO | claimed |
| US-20020173549-A1 | Compositions and methods for treatment of mild cognitive impairment | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-21 | — | — | US | claimed |
| EP-1253915-A1 | METHOD FOR TREATING STRESS WITH A PRECURSOR OF SEROTONIN | Massachusetts Institute of Technology (US) | 2002-11-06 | — | — | EP | claimed |
| WO-2002038141-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-05-16 | — | — | WO | claimed |
| WO-2001054681-A2 | COMPOSITION FOR TREATMENT OF STRESS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-08-02 | — | — | WO | claimed |
| US-10934429-B2 | Polycarbonate compositions having improved adhesion to polyurethane layers | COVESTRO DEUTSCHLAND AG (DE) | 2021-03-02 | — | — | US | disclosed |
| US-20190153218-A1 | POLYCARBONATE COMPOSITIONS HAVING IMPROVED ADHESION TO POLYURETHANE LAYERS | COVESTRO DEUTSCHLAND AG (DE) | 2019-05-23 | — | — | US | disclosed |
| US-4024050-A | Phosphorous ester antifoulants in crude oil refining | NALCO CHEMICAL COMPANY (US) | 1977-05-17 | — | — | US | disclosed |
| US-3974219-A | PREPARATION PEPTIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-08-10 | — | — | US | disclosed |