SCHEMBL8699875

SCHEMBL8699875

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.69
MAPT P10636 2/20 0.69
MEN1 O00255 1/20 0.69
LMNA P02545 1/20 0.69
MPO P05164 1/20 0.69
TSHR P16473 1/20 0.69
BLM P54132 1/20 0.69
PMP22 Q01453 1/20 0.69
KMT2A Q03164 1/20 0.69
HIF1A Q16665 1/20 0.69
HDAC8 Q9BY41 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NLN Q9BYT8 1/20 0.55
KRAS P01116 1/20 0.55
SOS1 Q07889 1/20 0.55
APAF1 O14727 1/20 0.54
POLB P06746 1/20 0.54
RECQL P46063 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
BCHE P06276 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8699883 1.00 KDM4E (0.69) KDM4EMAPTMEN1LMNAMPO
SCHEMBL7593998 0.95 KDM4E (0.63) KDM4EMAPTMEN1LMNAMPO
SCHEMBL30052868 0.91 KDM4E (0.60) KDM4EMAPTMEN1LMNAMPO
SCHEMBL29378473 0.90 KDM4E (0.65) KDM4EMAPTMEN1LMNAMPO
SCHEMBL18541537 0.90 KDM4E (0.65) KDM4EMAPTMEN1LMNAMPO
SCHEMBL16317501 0.90 KDM4E (0.65) KDM4EMAPTMEN1LMNAMPO
SCHEMBL9868659 0.90 OPRM1 (0.66) KDM4EMAPTMEN1LMNAMPO
SCHEMBL29391520 0.90 OPRM1 (0.66) KDM4EMAPTMEN1LMNAMPO
SCHEMBL31016727 0.89 KDM4E (0.58) KDM4EMAPTMEN1LMNAMPO
SCHEMBL20375720 0.89 KDM4E (0.64) KDM4EMAPTMEN1LMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695413-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 EP claimed
EP-4511052-A2 EPHRIN LIGAND MIMETIC PEPTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES University of Miami (US) 2025-02-26 EP claimed
US-20250042968-A1 EPHRIN LIGAND MIMETIC PEPTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES UNIV MIAMI (US) 2025-02-06 US claimed
WO-2024216031-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-10-17 WO claimed
EP-4424365-A2 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2024-09-04 EP claimed
EP-4017281-B1 PET FOOD COMPOSITIONS HILLS PET NUTRITION INC (US) 2024-08-28 EP claimed
CN-117003829-A Oil control polypeptide compound, preparation method and application thereof 成都凯捷多肽科技有限公司 2023-11-07 CN claimed
WO-2023205752-A2 EPHRIN LIGAND MIMETIC PEPTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES UNIVERSITY OF MIAMI (US) 2023-10-26 WO claimed
CN-114828648-A Pet food compositions 希尔氏宠物营养品公司 2022-07-29 CN claimed
EP-4017281-A1 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2022-06-29 EP claimed
EP-3947743-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2022-02-09 EP claimed
WO-2021127701-A1 PET FOOD COMPOSITIONS HILL'S PET NUTRITION, INC. (US) 2021-06-24 WO claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed
EP-0381997-A1 Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use Degussa Aktiengesellschaft (DE) 1990-08-16 EP claimed
JP-2023849-A None JP disclosed
JP-2004715-A None JP disclosed
US-12630631-B2 Inhibition of platelet aggregation using anti- human gpvi antibodies ACTICOR BIOTECH (FR) 2026-05-19 US disclosed
EP-0234186-A1 Use of oligopeptids for the treatment of cerebral disorders Fresenius AG (DE) 1987-09-02 EP disclosed
EP-0041935-B1 N-(VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS AND PEPTIDES AND THEIR PREPARATION OMNICHEM Société anonyme (BE) 1984-09-19 EP disclosed
EP-0041935-A1 N-(vinblastinoyl-23) derivatives of amino acids and peptides and their preparation OMNICHEM Société anonyme (BE) 1981-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630631-B2 Inhibition of platelet aggregation using anti- human gpvi antibodies IGLV6-57, GP6, VSIG8 KDM4E 4430/4885MAPT 4417/4885MEN1 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.