Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16062078 | 0.86 | MAPT (0.41) | FFAR4FFAR1MAPTALDH1A1 | |
| SCHEMBL2554110 | 0.80 | FFAR4 (0.44) | FFAR4FFAR1PPARALTB4R | |
| SCHEMBL29503795 | 0.77 | MAPT (0.43) | FFAR4FFAR1MAPTALDH1A1 | |
| SCHEMBL13382341 | 0.77 | TSHR (0.56) | MAPTALDH1A1 | |
| SCHEMBL12256336 | 0.76 | MAPT (0.37) | FFAR4FFAR1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL22390703 | 0.75 | CTSV (0.46) | MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL22390707 | 0.75 | CTSV (0.46) | MAPTALDH1A1 | |
| SCHEMBL634630 | 0.74 | FFAR4 (0.48) | FFAR4FFAR1 | |
| SCHEMBL30427829 | 0.74 | F13A1 (0.48) | FFAR4FFAR1MAPTALDH1A1 | |
| SCHEMBL4951982 | 0.72 | FFAR4 (0.45) | FFAR4FFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | claimed |
| CN-118510754-A | Novel isoindolinone derivative compounds as caspase inhibitors | 因诺沃治疗有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |