Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009647 | 0.98 | FFAR1 (0.44) | FFAR4FFAR1TSHRPPARACNR2 | |
| SCHEMBL3948951 | 0.85 | GRM2 (0.49) | FFAR4TSHRPPARACNR2 | |
| SCHEMBL1007343 | 0.84 | GRM2 (0.48) | FFAR4PPARACNR2 | |
| SCHEMBL6744367 | 0.79 | PKM (0.53) | FFAR1TSHRPTGDR2 | |
| SCHEMBL634919 | 0.78 | TSHR (0.43) | FFAR4FFAR1TSHRPPARARAB9A | |
| SCHEMBL8220579 | 0.78 | KDM4E (0.61) | PPARA | |
| SCHEMBL1008467 | 0.78 | LTB4R (0.47) | FFAR4FFAR1TSHRPPARA | |
| SCHEMBL13103839 | 0.78 | TSHR (0.65) | FFAR4FFAR1TSHRPPARA | |
| SCHEMBL10290763 | 0.77 | PPARA (0.51) | FFAR4FFAR1TSHRPPARA | |
| SCHEMBL1006920 | 0.77 | KDM4E (0.60) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306102-A1 | NOVEL SPIROOXYINDOLE COMPOUNDS AND DRUGS CONTAINING SAME | KOWA CO., LTD. (JP) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306102-A1 | NOVEL SPIROOXYINDOLE COMPOUNDS AND DRUGS CONTAINING SAME | HSD11B1, HSD11B2, HSD3B1 | FFAR4 239/4885FFAR1 152/4885TSHR 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.