Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 6/20 | 0.41 |
| ▸ | SDC2 | P34741 | 6/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25330548 | 1.00 | SDCBP (0.41) | SDCBPSDC2CASP1CASP3CASP7 | |
| SCHEMBL25330545 | 1.00 | SDCBP (0.41) | SDCBPSDC2CASP1CASP3CASP7 | |
| SCHEMBL25330876 | 0.93 | CASP1 (0.40) | SDCBPSDC2CASP1CASP3CASP7 | |
| SCHEMBL30477276 | 0.93 | CASP1 (0.40) | SDCBPSDC2CASP1CASP3CASP7 | |
| SCHEMBL25330880 | 0.93 | CASP1 (0.40) | SDCBPSDC2CASP1CASP3CASP7 | |
| SCHEMBL30477298 | 0.90 | MAPK1 (0.39) | SDCBPSDC2MAPK1 | |
| SCHEMBL25331706 | 0.89 | SDCBP (0.50) | SDCBPSDC2CASP3CASP7CASP8 | |
| SCHEMBL30477296 | 0.89 | SDCBP (0.50) | SDCBPSDC2CASP3CASP7CASP8 | |
| SCHEMBL25330941 | 0.89 | SDCBP (0.42) | SDCBPSDC2CASP3CASP7CASP8 | |
| SCHEMBL25330937 | 0.89 | SDCBP (0.42) | SDCBPSDC2CASP3CASP7CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4461726-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | Innovo Therapeutics Inc. (KR) | 2024-11-13 | — | — | EP | claimed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |