Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.42 |
| ▸ | SDCBP | O00560 | 6/20 | 0.40 |
| ▸ | SDC2 | P34741 | 6/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331038 | 1.00 | MAPK1 (0.42) | MAPK1SDCBPSDC2CREBBPCASP3 | |
| SCHEMBL25331331 | 0.95 | SDCBP (0.39) | MAPK1SDCBPSDC2CREBBPCASP1 | |
| SCHEMBL30477311 | 0.95 | SDCBP (0.39) | MAPK1SDCBPSDC2CREBBPCASP1 | |
| SCHEMBL30477324 | 0.88 | SDCBP (0.43) | MAPK1SDCBPSDC2CASP3CASP1 | |
| SCHEMBL25333877 | 0.88 | SDCBP (0.43) | MAPK1SDCBPSDC2CASP3CASP1 | |
| SCHEMBL25331706 | 0.87 | SDCBP (0.50) | MAPK1SDCBPSDC2CASP3CASP7 | |
| SCHEMBL30477296 | 0.87 | SDCBP (0.50) | MAPK1SDCBPSDC2CASP3CASP7 | |
| SCHEMBL30477317 | 0.85 | MET (0.42) | MAPK1SDCBPSDC2CASP1EGFR | |
| SCHEMBL25332196 | 0.85 | MET (0.42) | MAPK1SDCBPSDC2CASP1EGFR | |
| SCHEMBL25330487 | 0.85 | MAPK1 (0.43) | MAPK1SDCBPSDC2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4461726-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | Innovo Therapeutics Inc. (KR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |