Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30478349 | 0.78 | HRH4 (0.38) | SLC6A2HTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL30478207 | 0.78 | CHEK1 (0.38) | SLC6A3CHEK1 | |
| SCHEMBL30478356 | 0.78 | CHEK1 (0.38) | SLC6A3CHEK1 | |
| SCHEMBL1553284 | 0.72 | SLC6A2 (0.49) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL1961847 | 0.71 | SLC6A2 (0.50) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL28253269 | 0.70 | SLC6A2 (0.51) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL1552511 | 0.69 | SLC6A4 (0.43) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL1552430 | 0.69 | HTR1A (0.41) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL1551988 | 0.69 | HTR1A (0.41) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL1552724 | 0.69 | HTR1A (0.47) | HTR1ASLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452984-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Molecure S.A. (PL) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | disclosed |