Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | EED | O75530 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20281711 | 0.81 | HRH4 (0.42) | HRH4HRH3KDM1AEEDSLC6A2 | |
| SCHEMBL30478337 | 0.78 | ADRB2 (0.36) | HTR2AHTR2BCHEK1SLC6A2SLC6A4 | |
| SCHEMBL21607920 | 0.75 | HTR2C (0.41) | HRH4HRH3CACNA1HHTR2CHTR2B | |
| SCHEMBL20281811 | 0.73 | HRH4 (0.40) | HRH4HRH3KDM1ACACNA1HCHEK1 | |
| SCHEMBL20281731 | 0.73 | CACNA1H (0.40) | HRH4HRH3KDM1ACACNA1HHTR2A | |
| SCHEMBL20281715 | 0.73 | HRH4 (0.40) | HRH4HRH3KDM1ACACNA1HEED | |
| SCHEMBL21603171 | 0.73 | HRH4 (0.40) | HRH4HRH3KDM1ACACNA1HEED | |
| SCHEMBL23868365 | 0.72 | HRH4 (0.42) | HRH4HRH3KDM1A | |
| SCHEMBL20281629 | 0.72 | HRH4 (0.40) | HRH4HRH3KDM1ACACNA1HCHEK1 | |
| SCHEMBL27676209 | 0.71 | KDM4E (0.36) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452984-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Molecure S.A. (PL) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | disclosed |