SCHEMBL3047889

SCHEMBL3047889

C[C@@H](C(=O)O)N(C(=O)OCC1c2ccccc2-c2ccccc21)c1cscn1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.38
FABP7 O15540 2/20 0.38
KMT2A Q03164 2/20 0.36
MDM4 O15151 2/20 0.36
TP53 P04637 2/20 0.36
CASP3 P42574 2/20 0.36
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6629444 0.84 FABP5 (0.40) FABP5FABP7KMT2AMDM4TP53
SCHEMBL1905118 0.81 FABP5 (0.44) FABP5FABP7KMT2AMDM4TP53
SCHEMBL5966653 0.81 FABP5 (0.39) FABP5FABP7KMT2AMDM4TP53
SCHEMBL7443725 0.80 ALDH1A1 (0.39) KMT2A
SCHEMBL7443719 0.80 ALDH1A1 (0.39) KMT2A
SCHEMBL25303011 0.78 FABP5 (0.40) FABP5FABP7KMT2AMDM4TP53
SCHEMBL3821937 0.78 FABP5 (0.40) FABP5FABP7KMT2AMDM4TP53
SCHEMBL1885672 0.78 FABP5 (0.40) FABP5FABP7KMT2AMDM4TP53
SCHEMBL19668361 0.78 FABP5 (0.40) FABP5FABP7KMT2AMDM4TP53
SCHEMBL3821607 0.77 FABP5 (0.41) FABP5FABP7KMT2AMDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2026-01-22 US disclosed
US-20250250299-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2025-08-07 US disclosed
US-20250213705-A1 PSMA TARGETING LIGANDS AND METHODS OF USE BRIGHT PEAK THERAPEUTICS AG (CH) 2025-07-03 US disclosed
US-20250163104-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2025-05-22 US disclosed
WO-2025041103-A1 PSMA TARGETING LIGANDS AND METHODS OF USE BRIGHT PEAK THERAPEUTICS AG (CH) 2025-02-27 WO disclosed
US-20240409585-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2024-12-12 US disclosed
CN-111117812-B Environment-friendly sterilization composition and preparation method thereof 上海江笙生物科技有限公司 2021-04-13 CN disclosed
CN-111117812-A Environment-friendly sterilization composition and preparation method thereof 上海江笙生物科技有限公司 2020-05-08 CN disclosed
EP-3498289-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS Seattle Genetics, Inc. (US) 2019-06-19 EP disclosed
US-20180355025-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS INC. 2018-12-13 US disclosed
WO-2008140782-A2 COMPOUNDS FOR ENZYME INHIBITION PROTEOLIX, INC. (US) 2008-11-20 WO disclosed
EP-1948678-A1 COMPOUNDS FOR ENZYME INHIBITION Proteolix, Inc. (US) 2008-07-30 EP disclosed
EP-1917020-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS Seattle Genetics, Inc. (US) 2008-05-07 EP disclosed
WO-2007056464-A1 COMPOUNDS FOR ENZYME INHIBITION PROTEOLIX, INC. (US) 2007-05-18 WO disclosed
US-20070105786-A1 Peptide-based compounds include at least three peptide units, an epoxide or aziridine, and functionalization at the N-terminus inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases, e.g., the chymotrypsin-like activity of the 20S proteasome; antiproliferative and antiinflammatory agents PROTEOLIX, INC. (US) 2007-05-10 US disclosed
WO-2007008603-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2007-01-18 WO disclosed
US-20040082079-A1 Low affinity screening method GRAFFINITY PHARMACEUTICALS AG. (DE) 2004-04-29 US disclosed
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis ARIAD PHARMACEUTICALS INC. 2004-01-22 US disclosed
EP-1360489-A1 LOW AFFINITY SCREENING METHOD Graffinity Pharmaceuticals Aktiengesellschaft (DE) 2003-11-12 EP disclosed
WO-2002063299-A1 LOW AFFINITY SCREENING METHOD GRAFFINITY PHARMACEUTICALS AG (DE) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163104-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 FABP5 2427/4885FABP7 2559/4885KMT2A 2735/4885
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 FABP5 2537/4885FABP7 2103/4885KMT2A 1052/4885
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis SRC, CTTN, YES1 FABP5 2465/4885FABP7 4354/4885KMT2A 1865/4885
US-20240409585-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 FABP5 2253/4885FABP7 2379/4885KMT2A 2325/4885
US-20250213705-A1 PSMA TARGETING LIGANDS AND METHODS OF USE FOLH1, KLK3, PSMA2 FABP5 447/4885FABP7 347/4885KMT2A 2923/4885
US-20070105786-A1 Peptide-based compounds include at least three peptide units, an epoxide or aziridine, and functionalization at the N-terminus inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases, e.g., the chymotrypsin-like activity of the 20S proteasome; antiproliferative and antiinflammatory agents ANPEP, PSMB1, PSMB3 FABP5 4377/4885FABP7 3731/4885KMT2A 3318/4885
US-20180355025-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS MMAB, PTMS, DNPEP FABP5 882/4885FABP7 1499/4885KMT2A 1279/4885
US-20250250299-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 FABP5 2171/4885FABP7 2391/4885KMT2A 2293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.