Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464866 | 0.82 | TSHR (0.42) | SMN1; SMN2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL10711004 | 0.82 | TSHR (0.42) | SMN1; SMN2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15196486 | 0.82 | TSHR (0.42) | SMN1; SMN2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28023347 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL18721846 | 0.80 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28266559 | 0.78 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL9541723 | 0.78 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL1404146 | 0.78 | KLK7 (0.38) | SMN1; SMN2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL6129745 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL7456354 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772190-B2 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | BAYER ANIMAL HEALTH GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| US-20040034048-A1 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
| US-20020142969-A1 | DIDEPSIPEPTIDE-BASED ENDOPARASITICIDES, NEW DIDEPSIPEPTIDES AND PROCESS FOR PREPARING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | US | disclosed |
| CN-1053657-C | Didepsipeptide-based endoparasiticidal compositions, novel depsipeptides and methods for their preparation | BAYER AG (DE) | 2000-06-21 | — | — | CN | disclosed |
| CN-1199394-A | Didepsipeptide-based endoparasiticidal compositions, novel depsipeptides and methods for their preparation | BAYER AG (DE) | 1998-11-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034048-A1 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | VIP, NGLY1, NPEPPS | SMN1; SMN2 4170/4885CHRM1 4709/4885AKR1A1 4146/4885 |
| US-20020142969-A1 | DIDEPSIPEPTIDE-BASED ENDOPARASITICIDES, NEW DIDEPSIPEPTIDES AND PROCESS FOR PREPARING THE SAME | VIP, NGLY1, NPEPPS | SMN1; SMN2 4028/4885CHRM1 4706/4885AKR1A1 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.