SCHEMBL4464866

SCHEMBL4464866

CCC(OC(C)=O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
ALOX15 P16050 1/20 0.38
CHRM1 P11229 2/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
TBXA2R P21731 1/20 0.37
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GALR3 O60755 1/20 0.35
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15196486 1.00 TSHR (0.42) TSHRSMN1; SMN2ALOX15CHRM1CHRM2
SCHEMBL10711004 1.00 TSHR (0.42) TSHRSMN1; SMN2ALOX15CHRM1CHRM2
Benzene SCHEMBL3676205 0.95 SMN1; SMN2 (0.42) TSHRSMN1; SMN2ALOX15CHRM1CHRM2
Acetone SCHEMBL15323054 0.91 SMN1; SMN2 (0.36) TSHRSMN1; SMN2ALOX15CHRM1CHRM2
SCHEMBL18668942 0.84 SMN1; SMN2 (0.36) TSHRSMN1; SMN2ALOX15
SCHEMBL18668796 0.84 SMN1; SMN2 (0.36) TSHRSMN1; SMN2ALOX15LMNAGALR3
SCHEMBL18668881 0.83 SMN1; SMN2 (0.35) TSHRSMN1; SMN2ALDH1A1MAPTTDP1
SCHEMBL12314325 0.82 TSHR (0.43) TSHRSMN1; SMN2ALOX15CHRM1CHRM2
SCHEMBL12314349 0.82 TSHR (0.43) TSHRSMN1; SMN2ALOX15CHRM1CHRM2
SCHEMBL3047899 0.82 SMN1; SMN2 (0.41) SMN1; SMN2CHRM1TDP1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107200905-B A kind of micro-elasticity plastics sheep bed and its preparation method and application 山东阳春羊奶乳业有限公司 2019-08-13 CN claimed
CN-108271388-A Methionine produces 赢创德固赛有限公司 2018-07-10 CN claimed
CN-107325412-A A kind of sheep bed screen floor for manure and preparation method thereof 山东阳春羊奶乳业有限公司 2017-11-07 CN claimed
CN-107200905-A A kind of micro-elasticity plastics sheep bed and its preparation method and application 山东阳春羊奶乳业有限公司 2017-09-26 CN claimed
CN-104755510-A Ziegler-Natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORP LTD 2015-07-01 CN claimed
CN-1806846-A Chinese medicinal composition, its preparation process and quality control method BEIJING KAIRUI INNOVATION PHAR (CN) 2006-07-26 CN claimed
US-20060034645-A1 Magnetic roller sleeve for toner cartridge of printer PROWEAL COUNTER CORP. 2006-02-16 US claimed
CN-1660379-A Combination of medication, preparing method and method of controlling quality KAIRUI INNOVATION MEDICINE TEC (CN) 2005-08-31 CN claimed
EP-0168480-A4 PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID. WISCONSIN ALUMNI RES FOUND (US) 1987-10-08 EP claimed
EP-0168480-A1 PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1986-01-22 EP claimed
WO-1985003307-A1 PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1985-08-01 WO claimed
JP-7206672-A None JP disclosed
EP-4725944-A1 NEW METHOD FOR PREPARING OXOPYRIDINE COMPOUND, AND KEY INTERMEDIATE AND USE Chengdu Shibeikang Biomedical Technology Co., Ltd. (CN) 2026-04-15 EP disclosed
WO-2024251276-A1 NEW METHOD FOR PREPARING OXOPYRIDINE COMPOUND, AND KEY INTERMEDIATE AND USE 成都施贝康生物医药科技有限公司 2024-12-12 WO disclosed
CN-116535392-B Preparation method of oxo-pyridine compound, intermediate and application 成都施贝康生物医药科技有限公司 2023-09-05 CN disclosed
EP-0485723-A1 Hexitol derivatives KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1992-05-20 EP disclosed
US-4544623-A Photosensitive coating composition and the use thereof for protective purposes CIBA-GEIGY CORPORATION (US) 1985-10-01 US disclosed
US-4058541-A Preparation of 2-alkanoyloxy-alkanoic TEXACO INC. (US) 1977-11-15 US disclosed
US-4058540-A FROM A NITROALKYL NITRATE OR NITRO ALCOHOL AND ALKANOIC ACID, CALCIUM OCIDE OR CARBOXYLATE CATALYST TEXACO INC. (US) 1977-11-15 US disclosed
US-3980670-A Manufacture of methacrylic acid and butyrolactone BASF AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed