Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938305 | 0.85 | MCHR1 (0.56) | MCHR1ALDH1A1TSHRLMNACCR3 | |
| SCHEMBL30923249 | 0.84 | GRM5 (0.53) | MCHR1ALDH1A1TSHRLMNAGRM5 | |
| SCHEMBL30564259 | 0.81 | ALDH1A1 (0.56) | MCHR1ALDH1A1TSHRLMNACCR3 | |
| SCHEMBL1711687 | 0.78 | ALDH1A1 (0.63) | MCHR1ALDH1A1TSHRLMNAGRM5 | |
| SCHEMBL29530916 | 0.78 | ALDH1A1 (0.63) | MCHR1ALDH1A1TSHRLMNAGRM5 | |
| SCHEMBL30923253 | 0.78 | DDB1 (0.42) | MCHR1ALDH1A1TSHRLMNACCR3 | |
| SCHEMBL30479041 | 0.78 | POLB (0.40) | MCHR1ALDH1A1TSHRLMNACCR3 | |
| Hydrochloric Acid SCHEMBL31722313 | 0.77 | ALDH1A1 (0.62) | MCHR1ALDH1A1TSHRLMNAGRM5 | |
| SCHEMBL31487395 | 0.77 | CCR3 (0.39) | MCHR1ALDH1A1TSHRLMNACCR3 | |
| SCHEMBL31487411 | 0.77 | MCHR1 (0.39) | MCHR1ALDH1A1TSHRLMNACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |